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Jan 19, 1993 DNA-Unwinding Dynamics of Escherichia coli UvrD Lacking the C-Terminal 40 Amino Acids. Biophysical Journal 2020, 118 (7) , 1634-1648.
Product Class: Other Tte UvrD Helicase Need assistance designing LAMP primers? Use the NEB LAMP Primer Design Tool. Product Introduction Unwinds double-stranded DNA Thermostable to 65°C Reduces non-specific product Listen to Sugarless Kiss on Spotify. Suzuko Mimori · Song · 2021.
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2008-03-15 · UvrD from E. coli is a 73-kDa protein and was characterized as DNA helicase II (Kumura and Sekiguchi, 1984). UvrD and Rep belong to the SF1 family, which shares 40% amino-acid identity and these are remarkably similar to the PcrA helicase of Gram-positive bacteria. The uvrD gene of E. coli encodes a DNA-dependent ATPase. Nature 298:98-100; Arthur, H.M., P.B. Eastlake 1983. Transcriptional control of the uvrD gene of Escherichia coli. Gene 25:309-316; Easton, A.M., S.R. Kushner 1983.
Moreover, the two distinct activities correlate with the number of UvrD helicases present on the DNA hairpin, measured by counting singly labeled UvrD . When we observed frustrated unwinding activity, we usually detected only a single fluorophore, indicating a single UvrD loaded ( Fig. 2A , top panel).
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UvrD may refer to: UvrABC endonuclease, an enzyme DNA helicase, an enzyme class ‹ The template below (Disambiguation) is being considered for merging.
UvrD also participates in the UvrABC nucleotide excision repair pathway by removing the 12–13-base oligonucleotide containing a pyrimidine dimer or bulky adduct (3). Additional functions for UvrD have been proposed, consistent with the pleiotropic nature of uvrD mutants (4, 5, 7), including roles in replication and recombination (8–12). Product Class: Other Tte UvrD Helicase Need assistance designing LAMP primers? Use the NEB LAMP Primer Design Tool.
Our pieces not only encourage your unique expression, but they’re also a gift that keeps on giving. KUVRD’S products support refugee camps through providing meals and creating jobs. Using advanced solution NMR spectroscopy, Kawale and Burmann show that the carboxy-terminal region of the UvrD helicase adopts a Tudor-domain like fold to facilitate its interaction with RNA
Status. Unreviewed - Annotation score: Annotation score:2 out of 5. The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome.
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6). UvrD also participates in the UvrABC nucleotide excision repair pathway by removing the 12–13-base oligonucleotide containing a pyrimidine dimer or bulky adduct (3). Additional functions for UvrD have been proposed, consistent with the pleiotropic nature of uvrD mutants (4, 5, 7), including roles in replication and recombination (8–12).
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UvrD, a highly conserved helicase involved in mismatch repair, nucleotide excision repair (NER), and recombinational repair, plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species.
Suzuko Mimori · Song · 2021. Dec 29, 2006 UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke · Summary. Helicases use the energy derived from nucleoside Synonyms, uvr502; srjC; uvrE; dar-2; dda; mutU; pdeB; rad; recL. Accession IDs, EG11064 (EcoCyc) b3813.
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2008-03-15 · UvrD from E. coli is a 73-kDa protein and was characterized as DNA helicase II (Kumura and Sekiguchi, 1984). UvrD and Rep belong to the SF1 family, which shares 40% amino-acid identity and these are remarkably similar to the PcrA helicase of Gram-positive bacteria.
The UvrB still remains in place even though UvrC has disassociated at this stage, as UvrB may be involved to prevent the reannealing of the excised DNA. 2018-05-01 · RecF and UvrD proteins suppress DNA degradation and promote E. coli gamma-survival. • RecF and UvrD act in one pathway, which depends on RecA protein and SOS induction. • Acting alongside RecF, RecX suppresses DNA degradation and stimulates gamma-survival. • RecN suppresses DNA degradation, acting in the RecABCD pathway.